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HERDIN Record #: 108931-20082606593057 Submitted: 26 August 2020 Modified: 26 August 2020

Risk Factors Associated with Acute Kidney Injury in Neonates and Infants Following Open Heart Surgery.

Kristine Gay S. Tria,
Ma. Angeles G. Marbella

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BACKGROUND: The complexity of surgical cardiac procedures is on the rise, resulting in prolonged cardiopulmonary bypass time and stay in the intensive care unit. One major complication of cardiac surgery is acute kidney injury. The aim of this study is to investigate the incidence and risk factors associated with acute kidney injury following open heart surgery.

METHODOLOGY: This is a retrospective cohort study that involved chart review of patients ​

RESULTS: Sixty one (61) patients were included in the study. Nine patients (15%) developed post-operative acute kidney injury, two of which underwent peritoneal dialysis. Lowest systolic blood pressure and lowest mean arterial pressure were noted to be significant in the development of acute kidney injury with odds ratio of 0.95 (p=0.049) and 0.93 (p=0.025), respectively. The duration of mechanical ventilation was also significantly increased in patients who developed acute kidney injury (p=0.028).

CONCLUSION: Lowest systolic blood pressure and lowest mean arterial pressure are significant risk factors for acute kidney injury in neonates and infants following open heart surgery.

KEYWORDS: acute kidney injury, acute renal failure, cardiac surgery in infants, congenital heart disease, cardiopulmonary bypass time

Publication Type
Publication Sub Type
Journal Article, Original
Philippine Journal of Cardiology
Biennial (every 2 years)
Publication Date
July-December 2020
LocationLocation CodeAvailable FormatAvailability
Philippine Heart Association Abstract pdf (Download)